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Principal IS Application Analyst

Dana-Farber Cancer Institute
FULL_TIME Remote ยท US Boston, Massachusetts, US Posted: 2026-05-11 Until: 2026-07-10
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Job Description
Job Ref:JR-1338 Location:450 Brookline Ave, BOSTON, MA 02215 Category:IT/Informatics Employment Type:Full time Work Location:Remote: occasional onsite Salary/Pay Rate:$127,700.00 - $141,600.00 per year Overview This Principal IS (Information Systems) Application Analyst supports DFCI Information Services department systems and applications. The IS Principal Application Analyst will lead application deployment, configuration, system upgrades and maintenance for the many applications within the department. The role will continuously develop and implement process improvements that focus on optimizing operational efficiency, patient safety, and the quality of care. These functions are accomplished through participation in departmental projects with interdisciplinary teams that focus on workflow efficiency, clinical procedures, and applications training. Additionally, the IS Principal Application Analyst position requires a strong understanding of clinical workflows, excellent analytical and communication skills, and experience working with technical systems and interfaces.Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Primary Duties and Responsibilities Application Duties Conduct thorough evaluations of current software applications to assess functionality, performance, and user satisfaction. Identify and document shortcomings or areas for improvement within existing applications to better meet organizational needs. Serve as the top technical and functional subject-matter expert; resolve the highest-severity incidents, perform root cause analysis, and implement preventative controls and resiliency patterns. Own enterprise-level application domains and cross-application architecture; define and steward standards for configuration, integrations, data, security, testing, and release management. Project Leadership and Collaboration Translate business strategy into application roadmaps; partner with product owners and business leaders to prioritize portfolio and backlogs based on value, risk and feasibility. Work closely with customers to define business needs and develop project work approach, scope and timeline to meet both system and operational objectives. Participate in IS and clinical department projects, system upgrades and system enhancements utilizing standard project lifecycle tools and methodologies. Process Improvement Lead and supports process improvement and new technology initiatives Continual evaluation of existing workflows to identify inefficiencies and areas of improvement. Explores external vendors and internal resources for improvement opportunities surrounding clinical department applications, and operational support. Define and track KPIs/OKRs for application performance, reliability, and adoption; champion continuous improvement and post-implementation value realization. Training Duties Collaborate to design and implement training and professional development activities so that work is conducted in thoughtful planned manner Triage and prioritize training requests and recommend appropriate instructional methods such as individual or group instruction, lectures, online learning, hands-on workshop, or printed materials. Serve as Administrator for online learning management system (e.g. HealthStream). May include managing accounts, creating and maintaining online courses and curricula, running and analyzing reports, and leading troubleshooting when necessary. Vendor and Stakeholder Management Manage vendor relationships for critical platforms; evaluate solutions, influence vendor roadmaps, oversee escalations, and ensure contractual SLAs and support models meet business needs. Align support efforts with organizational IT and clinical operations. Knowledge, Skills and Abilities Deep expertise across multiple enterprise applications and modules, including advanced configuration, workflow design, and end-to-end solution integration. Skilled at managing and implementing change, particularly in quality improvement