Job Description
Key responsibilities Culture, quality control (QC), and cell banking of diverse solid tumor cell lines Engineer, culture and characterize CAR T cell function in vitro Perform routine laboratory procedures including ddPCR, qPCR, Flow, Luminex/MSD for ELISA and various cell-based immunoassays and biochemical assays Analyze, interpret, and translate results into actionable and tangible findings Maintain accurate and detailed records of laboratory procedures, experimental designs, and results in compliance with organizational standards; familiarity with Benchling a plus. Design and execute fit-for-purpose or hypothesis-based experiments; analyze and interpret data to support development Communicate effectively research plans and results, in both oral and written form Coordinate tasks across multiple projects, work closely with cross-functional teams to support ongoing research projects, ensuring seamless integration of experimental findings Contribute to a dynamic, exciting culture that embraces teamwork and innovation Support the timeline-sensitive Pre-IND/IND research activity and work cross-functionally with different teams Basic Qualifications Master’s Degree and 2+ years of related industry/academic Experience OR Bachelor’s Degree and 4+ years of related industry/academic experience OR Preferred Qualifications BS 6+ years or MS 3+ years or equivalent degree of relevant experience in Cell Biology and/or Immunology. Prior hands-on experience in the CAR-T field is preferred. Proficiency in experiment design, data analysis, interpretation, and presentation. Required high degree of accuracy and attention to details. Hands on experience with primary T cell isolation, culture and assays (e.g. cytotoxicity assays, cell proliferation assays, xCELLigence/eSight assays), multicolor flow cytometry, SCLC cell line culture and data analysis (FACSDiva, FlowJo, GraphPad, Prism, Excel). Experience with ex vivo CAR T manufacturing is preferred Strong communication skills, both written and verbal. The ideal candidate should be flexible to meet team’s priorities and willing to support team members with their projects.