Job Description
Title: Scientist Location: Ridgefield, CT Contract : 24 months Contributes to design and execution of in vivo studies relevant to cardio-renal metabolic diseases (kidney injury, cardiovascular and metabolic driven cardio-renal dysfunction.) Perform dosing procedures (oral gavage, IP/IV/SC injections), physiological monitoring, and sample collection (blood, urine, tissues). Conduct functional assessments, such as blood pressure measurements, echocardiography support, telemetry, metabolic cage studies, and renal function assays. Process and analyze biological samples, including histology, biomarker assays, qPCR, ELISA, and other molecular or biochemical readouts. Maintain high-quality documentation, including study protocols, animal records, raw data, and reports compliant with internal and regulatory standards. Collaborate cross functionally with pharmacology, pathology, bioanalytics, and therapeutic area biology teams to interpret data and refine study designs. Ensure compliance with IACUC protocols, ethical animal care standards, and institutional guidelines. Contribute to scientific discussions, present data at team meetings, and support preparation of internal reports and external publications. Requires moderate physical activity to perform work in the vivarium and laboratory, including (but not limited to) standing for extended durations (>2 hours), working under a biosafety hood/cabinet for extended durations (>2 hours), bending, lifting (up to 20 lbs), squatting, pushing/pulling, and reaching. Also requires daily handling and restraint of small laboratory animals (rats, mice; >50 at a time), often within a specified timeframe. Requires use of personal protective equipment (PPE), including respiratory, eye, hand, and foot protection. Ability and willingness to work effectively in a highly collaborative environment and support weekend work as need