Senior Director, Technical Accounting & SEC Reporting

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH. Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c). Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way. The Senior Director, Technical Accounting & SEC Reporting will serve as the company’s subject-matter expert on U.S. GAAP and SEC reporting requirements, partnering closely with Finance leadership, independent auditors, and cross-functional stakeholders to ensure accurate financial reporting and compliance. This role serves as a global steward and owner of accounting policies and will advise on technical accounting considerations and /or requirements as business activities or transactions being contemplated. This leader will own key controls over financial reporting. Role scope will include consolidation of financial results, submission of SEC filings, and underlying systems and research tools. This role will report to the Chief Accounting Officer and partner closely with the CFO, and members of the finance, legal, and HR leadership teams. Key Responsibilities Lead technical accounting assessments for transactions, including: Revenue recognition, collaboration and licensing arrangements Stock-based compensation Business combinations R&D cost accounting, including CRO arrangements and prepaid R&D Leases Draft and maintain technical accounting position papers for global finance team Own timely preparation and detailed review of SEC filings (i.e. 10-K, 10-Q, 8-K, DEF 14A), including accounting treatment and disclosures of: MD&A Critical accounting estimates Revenue R&D disclosures (i.e. pipeline acquisitions and IPR&D) Licensing, collaboration, and co-commercialization agreements EPS Advise leadership on accounting considerations during deal structuring Provide technical accounting guidance to global stakeholders for topics including: Licensing, collaboration, and co-commercialization agreements M&A transactions Financing and complex capital structures Provide SEC reporting and technical accounting leadership to the Treasury function on equity and debt offerings, including reviewing offering documents and supporting due-diligence and auditor comfort letter processes Partner with Investor Relations to ensure alignment between GAAP and non-GAAP (if applicable) reporting across SEC filings, supplemental reporting, and other investor-facing materials, including investor Q&A Articulate issues and recommendations in a crisp and concise manner to both financial and non-financial stakeholders for consideration in decision-making Assist in the review of accounting considerations from the execution of significant contracts Partner with Legal, FP&A, Tax, Investor Relations on accounting implications of significant transactions and/or ad hoc initiatives Co-develop disclosure committee agenda topics with Legal partners Perform benchmarking to peer disclosures, review leading disclosure practices for emerging risks, business activities, and newly adopted accounting standards Consolidation of Financial Results Oversee the timely consolidation of financial results, including as needed preparation of journal entries, account reconciliations, and variance analysis Audit & SOX Compliance Serve as primary liaison with independent auditors on technical accounting and audit discussions related to significant non-routine transactions Coordinate audit requests, prepare supporting documentation, and resolve audit inquiries for quarterly reviews and annual audits Assume ownership for effective key internal controls over financial reporti