Job Description
Work Location: Billerica, Massachusetts Shift: No Department: HC-RD-XO4 Oligonucleotide Chemical Conjugation Recruiter: Beverly Dellisola This information is for internals only. Please do not share outside of the organization. Your Role: EMD Serono in Billerica, MA is seeking a Senior Scientist - Oligo Bioinformatics to add to their Oligonucleotide Therapeutics Group (DDTech). Responsibilities Develop pipelines that determine mapping coordinates and homology of oligonucleotides to genomes and transcriptomes Design and build pipelines that process and analyze related data, store summary results and integrate with the corporate ELN Develop pipelines that determine mapping coordinates and homology of oligonucleotides to genomes and transcriptomes Develop, deploy, manage, and run applications using Docker containers Discovery and development of oligonucleotide therapeutics Who You Are: Minimum Qualifications: PhD in Chemistry, Chemical Engineering, Computer Science or other Science field with 3+ years of direct experience in siRNA/ASO/SSO Preferred Qualifications: Experience with common human genetics resources and techniques Deployment of interactive applications from scripting languages like R and Python (Shiny and streamlit) Experience with relational databases; hands on experience with MySQL Experience in common NGS analyses task such mapping reads, quantification of gene expression, and/or variant calling Experience with common bioinformatics tools like Samtools, GATK, Bowtie, HISAT2, BLAST, htseq-count, DESeq, Salmon, STAR, or Subread Knowledge of Illumina sequencing data analysis is necessary and experience with PacBio and/or Nanopore sequencing Familiarity with UNIX computing environ